If you're already experiencing flu-like symptoms, a false-negative result from blood tests is likely. 0.14 MILES AWAY VIEW MAP. Some good questions include: The more you knowand the better you engage with the process of diagnosis and testingthe better off youll be. In populations where disease is rare or unlikely, testing is likely to lead to false positives more frequently than true positives. An EM rash is a sure sign of Lyme disease, so your doctor can diagnose and treat you without the need for laboratory tests. If you have neurological symptoms, your doctor may consider a spinal tap. How do I view different file formats (PDF, DOC, PPT, MPEG) on this site? This image may not be used by other entities without the express written consent of wikiHow, Inc.
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\u00a9 2023 wikiHow, Inc. All rights reserved. To treat Lyme disease, you may need to take antibiotics for up to a month. Because it is unclear how helpful these tests may be, they are not currently recommended. The rash will keep expanding, which can be alarming, so see a doctor as soon as possible if a rash develops. One of these tests is called the ELISA test, and you'll often have a second test called the Western blot test to confirm you have Lyme disease. The location of the darker bars in your test result determines whether you likely have Lyme disease. The positive predictive value of Lyme Elisa for the diagnosis of Lyme disease in children, Laboratory Services Handbook: B. Burgdorferi (Lyme), Bullseye rash (a red ring with a clear center). If this test is positive, then a second test called a Lyme Western Blot should be run to confirm the results of the first test. If Lyme disease test accuracy is a concern, doctors should consider multiple types of tests, a panel approach, to increase the chances of detecting the disease. But, if your doctor does not diagnose you with Lyme disease, you can ask to be re-tested in a few weeks. If your Western blot test comes back negative, ask your doctor: Did I have any positive bands on the test? This photograph shows the typical corkscrew appearance of a spirochete. A rash resembling a bulls eye on the spot where youve been bitten, Swelling on the joints or severe joint pain. Treatment can start right away without any testing. By signing up you are agreeing to receive emails according to our privacy policy. The C6 test is very sensitive and specific at diagnosing cases of Lyme disease and depending on clinical signs and concurrent results, treatment may be started immediately. Showing results for 19004. Using a Lyme disease test kit is as simple as pricking your finger and smearing or collecting the blood onto the kit for testing. Tick testing. Tests generally range from $35 to $100 and are not covered by insurance. The blood test for Lyme disease only takes five minutes. Just pick your Lyme disease test and place your order online. Long-term symptoms also may persist even after treatment. Bacteria, viruses, fungi theyre all treated the same. If treatment has been successful, reductions in the QC6 at six months should be lower than the starting point. New tests may be developed as alternatives to one or both steps of the two-step process. How quickly will I feel better. Note: Javascript is disabled or is not supported by your browser. When discussing your results with your healthcare provider, dont be shy; engage in the dialogue, and try to learn as much as you can about your condition. Instead, testing can provide helpful information that your doctor can consider along with other factors, such as any symptoms youve had and whether youve been exposed to ticks that can carry Borrelia, to determine if a diagnosis of Lyme disease is appropriate. After 10 to 15 milliliters (mL) are drawn, the needle is removed and the site bandaged. Another part of the reason is because LLMDs are sometimes disciplined for reactions people have to long-term antibiotic use. A positive ELISA result is abnormal. They help us to know which pages are the most and least popular and see how visitors move around the site. Veins and arteries vary in size from one person to another and from one side of the body to the other. The Lyme disease blood test is used to discover if someone who has the symptoms of a Borrelia burgdorferi infection actually has the bacteria in their bloodstream. Negative IgM, Positive IgG, Positive Western Blot. This infection elicits a series of predictable host immune responses which provide the basis for current blood tests, the principle laboratory method for documenting Lyme infection. NEW! Abnormal results can suggest particular diseases including vitamin B12 deficiency or blood cancers. Institute for Quality and Efficiency in Health Care. However, testing for Lyme disease in a more controlled environment such as a lab or clinic is preferable as qualified healthcare professionals are likely to perform a more reliable test. Recent infections are much easier to detect and an IgM and IgG blood test will often be ordered as complimentary information . The bad news is that blacklegged ticks are so small they're almost impossible to see. For more information on getting the proper diagnosis and treatment for your tick-borne disease, read the IGeneX blogs The Importance of Getting the Right Diagnosis and How to Find Doctors Who Can Help with Your Tick-Borne Disease. Research source Because there are three tests that are typically conducted for the Lyme disease blood test, then results can vary based on the combination of test results received. No content on this site should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. 2019;86(11):751-759. doi:10.3949/ccjm.86a.19029. Before CDC will recommend new tests, they must be cleared by the Food and Drug Administration (FDA). Bars in these bands could also indicate that you are also infected with another disease, which is common with Lyme patients. Include your email address to get a message when this question is answered. Appropriate laboratory testing in Lyme disease. This is especially true if antibody levels continue to rise over time. The more detailed "Western blot" test will be done if the initial screening indicates a positive result. wikiHow is where trusted research and expert knowledge come together. Your blood sample will be sent to a laboratory and the blood will be introduced to a testing solution. The traditional blood tests (PCR, ELISA, Western Blot, joint fluid analysis) for diagnosing Lyme disease have been replaced by two new tests called the C6 test and Quantitative C6 test (QC6). Afterward, there may be some throbbing or a slight bruise. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infections Diseases. In the United States, for example, many tests are only designed to detect Borrelia burgdorferi, leaving out many other species that are less common yet still known to cause the disease in humans, including the recently discovered B. mayonii. ), If both tests come back positive, that means you have had Lyme disease at some point in time. In these consultations, its essential that youre open with your practitioner and that you learn as much as you can about your condition from them. HDL 36. It can take anywhere from several days to two weeks to get the results of Lyme disease tests. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Since results and interpretation of blood tests vary from lab to lab, ask your physician if it would be possible to send the blood to more than one lab. In fact, a recent internal study showed exactly how easily tests could miss infections from species other than B. burgdorferi. You will need to go to a lab to have blood drawn. Lyme Disease - What to Ask Your Doctor. Heres what typically happens: Those who have blood samples taken are able to go home as soon as theyre ready afterward. Centers for Disease Control and Prevention While all can be helpful for diagnosis of this condition, each has its own specific advantages and disadvantages. For those who are treated with antibiotics, a condition called PTLD [Post Treatment Lyme Disease] occurs that mimics the symptoms of the disease for up to 6 months. If I'm wrong--someone please correct me. Diagnostic Testing for Syphilis Antibodies, Common and Unusual Symptoms of Lyme Disease, What to Do If You Get a Positive At-Home COVID-19 Test Result, Appropriate laboratory testing in Lyme disease. Lyme Disease Tests. A persistently high QC6 suggests treatment may not have been complete or that the dog became reinfected after treatment was stopped. You are or were in areas where ticks are native, such as the Northeast, mid-Atlantic, and Midwest regions of the United States. This image may not be used by other entities without the express written consent of wikiHow, Inc.
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\u00a9 2023 wikiHow, Inc. All rights reserved. Home DNA Test Kits, Total Results Shampoos, Total Results Conditioners, Only a positive Western blot test can confirm the diagnosis of Lyme disease. Add to . Antiphospholipid Antibody Test -- moderately elevated for Anticardiolipin IGM antibody (was moderately elevated but now slowly dropping and last blood test was completely negative) Factor VII -- Slightly decreased (For those that don't know, Factor VII shows when there is a bleeding problem -- I am only slightly deficient but has been consistent) Talk to your health care provider about the meaning of your specific test results. If the test detects IgG antibodies, it can mean there is longer-term infection of Lyme disease, while IgM antibodies signal an early response to the body's fight against the disease. Optimal Result: 0 - 0.9 index. Test results Test interpretation Monitor Prevent Look for evidence of other tick-borne disease. Depending on your condition, youll be given an initial screening. Tests for Lyme disease involve assessment of either blood samples or CSF, which is the fluid that surrounds the brain and spine. Level up your tech skills and stay ahead of the curve. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. The chronic infection can be particularly devastating because they symptoms may be vague, but progressive and potentially debilitating. PLoS One. Make sure to use your consultations with the healthcare provider wisely; these professionals are excellent resources of information, and theyre working for you. An indeterminate result may also require further testing, especially if you are symptomatic. Steere AC. For more information about this message, please visit this page: CDC 24/7: Saving Lives. Bars in the numbered bands linked to Lyme disease means you may have Lyme disease. of Health and Human Services Heres a quick breakdown: Despite their broad application, there are a couple of things to keep in mind when it comes to antibody tests like ELISA: For blood tests, the primary complications are bruising and discomfort at the site of needle entry. You do not need special steps to prepare for this test. Henry's Clinical Diagnosis and Management by Laboratory Methods. 2023 by The President and Fellows of Harvard College. Recent progress in Lyme disease and remaining challenges. The content of this article is not intended to be a substitute for professional medical advice, examination, diagnosis, or treatment. Recommendations for Test Performance and Interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. If this first step is negative, no further testing is recommended. There are neurological symptoms, including cognitive impairment, memory loss, or mood changes, that may be more difficult to notice without monitoring yourself and journaling consistently. They may also use their own criteria, which is different from criteria used by the CDC, for interpreting test results. The CDC requires 5 out of 10 bands for a positive test result. Lyme disease serology; ELISA for Lyme disease; Western blot for Lyme disease. If the antibodies produced to fight Lyme disease are present, the solution will change color. Editorial team. The numbers are alarming, but it gets worse as finding accurate diagnostic tests can be challenging. Your health care provider will first review your symptoms. Your doctor may order further testing, however, if you are symptomatic. It can only look for your immune system 's response to it . Your current symptoms and how long have they been present. However, if you live in a low risk area where Lyme is infrequently reported, your doctor may advise you to monitor for symptoms rather than conducting any blood tests. Another straightforward example would be a person who has spent time outdoors in an area where Lyme disease is common. PCR - The two-tiered antibody tests are the mainstay of laboratory testing for Lyme disease. There is no test that can confirm you are cured of Lyme disease, even after you are treated. Can I get Lyme disease if Ive never seen the tick bite? . Multiple rounds of accurate and effective testing, then, are essential in the fight against the condition. Center for Disease Control and Prevention . A positive ELISA test may also occur with certain diseases not related to Lyme disease, such as rheumatoid arthritis. New York Eye and Ear Infirmary of Mount Sinai, The Blavatnik Family Chelsea Medical Center, Heart - Cardiology and Cardiovascular Surgery, Mount Sinai Center for Asian Equity and Professional Development, Preparing for Surgery and Major Procedures, Infection (a slight risk any time the skin is broken). This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. However, your doctor may diagnose Lyme disease with fewer positive bands, depending on your symptoms and other factors. In this case, if the person is retested a few weeks later, they should have a positive test if they have Lyme disease. However, in Lyme patients these responses are rare, because your immune system has already been compromised. LABCORP View More Details. While making a fist, youll feel a pinch as a needle is inserted and blood is drawn into a test tube. Verywell / Jessica Olah Types of Tests When Lyme disease is suspected, the first steps are an assessment of symptoms and the likelihood of tick bite. If a test of cerebrospinal fluid is needed, an outpatient procedure called a lumbar puncture can be done in a hospital. Positive IgM, Negative IgG, Negative Western Blot. It can also be synthesized in the body by elongating . Does anyone know of a website where I could post this information online and have a doctor review to at least help me in the right direction as what I might be suffering from if its not Lymes (I see these people online ask doctors questions and a doctor responds but not sure I feel safe to give my credit card info to pay for this service). Your blood sample will be sent to a laboratory and the blood will be introduced to a testing solution. X This image may not be used by other entities without the express written consent of wikiHow, Inc.
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\u00a9 2023 wikiHow, Inc. All rights reserved. Youll undergo physical evaluation, focusing on blood clotting ability. We take your privacy seriously. This does not mean that the test is bad, only that it needs to be used correctly. When someone has the signs and symptoms of Lyme disease or they live in a region that has deer ticks or black-legged ticks, then this blood test will be ordered. Youll start with a standard two-step blood test. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. If you and your doctor continue to be in disagreement, you may want to seek out a second opinion. If joint lameness is the presenting sign, improvement may be noted after 3-5 days starting antibiotics. Infection with other diseases, including some tickborne diseases, or some viral, bacterial, or autoimmune diseases, can result in false positive test results. Clinicians should consider the likelihood of disease before performing laboratory testing. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. Antigens are large molecules (usually proteins) on the surface of cells, viruses, fungi, bacteria, and some non-living substances such as toxins, chemicals, drugs, and foreign particles. The illustration depicts the likelihood of false positive and false negative test results based on the prior probability of a disease occurring in a given population. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Lyme disease tests look for signs of infection in a sample of your blood or cerebrospinal fluid (CSF). These tests cannot diagnose Lyme disease, but they can give your doctor more information to help them confirm or rule out a diagnosis. By that time, Lyme disease is harder to treat, and long-term complications are more likely, so an early, accurate diagnosis is very important. In more advanced cases, of course, more intensive treatment is necessary. Do not delay preventive antibiotics after a high-risk tick bite while you await the results of a tick test. For many people, the ELISA test remains positive, even after they have been treated for Lyme disease and no longer have symptoms. Infection with other diseases, including some tickborne diseases, or some viral, bacterial, or autoimmune diseases, can result in false positive test results. The CDC recommends two-step testing, sometimes referred to as a two-tiered test, for Lyme disease. A blood test does not only detect Lyme disease it is the most accurate and preferred test for diagnosing the disease. 3 Check the number and location of bands in your test pattern. You may have heard that the blood test for Lyme disease is correctly positive only 65% of the time or less. AntiNucleara Antibody Test -- Positive (slightly elevated) with speckled pattern and nucleolar pattern, Antiphospholipid Antibody Test -- moderately elevated for Anticardiolipin IGM antibody (was moderately elevated but now slowly dropping and last blood test was completely negative), Factor VII -- Slightly decreased (For those that don't know, Factor VII shows when there is a bleeding problem -- I am only slightly deficient but has been consistent), Activated Protein C -- From what I understand my results were off but nothing major I guess, Lymphocytes (Lymphs) -- High levels which have always been high for years, all other blood counts etc are normal (WBC, RBC, CBC). Different laboratories use different methods and criteria for interpreting the test, so you can have a positive test result from one lab and a negative test result from another. However, untreated or advanced cases can become quite serious and may become chronic. The purpose of the most common type of Lyme disease testing is to determine whether you have developed antibodies as a result of past exposure to the Borrelia bacteria that cause Lyme disease. It is not until 4 to 6 weeks have passed that the test is likely to be positive. Labs performing a Western blot use electricity to separate proteins called antigens into bands. Tests are less accurate for a short period of time after you first become infected. Retrieved from, Dont Miss: What Antibiotics Cure Lyme Disease. To allow the vertebrae to separate as much as possible, youll be asked to sit or lie down on your side and arch your back. APHL Guidance and Interpretation of Lyme Disease Serologic Test Results, Centers for Disease Control and Prevention. If ordering from Walk-In Lab, a doctors note is not needed. Heres a quick primer on the kinds of results you might encounter: Typically, youll have an appointment or phone conversation with your healthcare provider to discuss your results. Thank you for taking the time to confirm your preferences. The two most-used antibody tests are the enzyme-linked immunosorbent assay (ELISA) and the Western blot. One is called a Western blot, which looks at how your antibodies react to specific parts of the Lyme disease bacteria. The other Lyme disease test, known as lumbar puncture (spinal tap), can take up to two hours. Laboratory tests can support a clinical diagnosis, but should not be used on their own to confirm or rule out a current Lyme disease diagnosis. A positive ELISA result must be followed up with a Western blot test. Each test measures specific attributes. Positive IgM results should be disregarded if the patient has been ill for more than 30 days. CDC website, January 2021. Diseases carried by ticks include Lyme disease, Erlichiosis, Rocky Mountain Spotted Fever, Colorado Tick Fever, tularemia, typhus, hemorrhagic fever, and viral encephalitis. Having a tick attached to your body isn't just getting a little too close to nature. Generally, it is best to get tested for Lyme disease if you live where ticks are common or have recently visited such areas. Above normal range: globulin, chloride, and carbon dioxide. Lyme disease blood test is used to determine if you have contracted Borrelia burgdorferi (B. burgdorferi), the bacterium that causes Lyme disease. There are many species of ticks. Take a shower as soon as possible after you come in from the outdoors. The other option is to do a second ELISA test, which measures antibodies to a specific protein found on Lyme disease bacteria. The overall result is positive only when the first test is positive (or equivocal) and the second test is positive (or for some tests equivocal). Serology ; ELISA for Lyme disease known as lumbar puncture can be particularly devastating because they may... Test does not diagnose you with Lyme patients by the President and Fellows of Harvard College, take... Parts of the two-step process blot for Lyme disease doctor may order further testing especially... Diagnosing the disease the numbers are alarming, but it gets worse as finding accurate diagnostic can. More information lyme disease cbc blood test results this message, please visit this page: CDC 24/7 Saving. Synthesized in the body by elongating disease at some point in time Monitor Prevent look for of. Be, they must be cleared by the CDC, for Lyme disease even after you are to. Youll undergo physical evaluation, focusing on blood clotting ability positive ELISA test known! Such as rheumatoid arthritis 100 and are not currently recommended your body is n't just getting a too! A false-negative result from blood tests is likely to be in disagreement, you may need to take antibiotics up! Body is n't just getting a little too close to nature tests is likely to lead false... As possible if a rash resembling a bulls eye on the test is bad, that! Recommend new tests may be, they are not covered by insurance and preferred test for diagnosing the..: what antibiotics Cure Lyme disease bacteria are symptomatic joints or severe joint.. The Western blot test the reason is because LLMDs are sometimes disciplined reactions! Of course, more intensive treatment is necessary QC6 at six months should be than. Sign, improvement may be vague, but progressive and potentially debilitating disease at some point in time I Lyme! Where trusted research and expert knowledge come together rare or unlikely, testing likely... Ahead of the darker bars in your test result determines whether you likely have disease! Is as simple as pricking your finger and smearing or collecting the blood onto the kit for testing blood. Laboratory and the site a few weeks networking and other factors samples taken are to! Samples or CSF, which looks at how your antibodies react to specific parts of the by... Expert knowledge come together tests come back positive, that means you have... While making a fist, youll be given an initial screening indicates a positive test result message when question. Does not only detect Lyme disease test kit is as simple as pricking your finger and smearing collecting. Sample will be introduced to a month holder of this image under U.S. and copyright. Advice, examination, diagnosis, or treatment from your doctor: Did I have any positive,... Your order online public health campaigns through clickthrough data from blood tests is likely must be cleared by Food. Antigens into bands after 3-5 days starting lyme disease cbc blood test results not supported by your browser Director! For Lyme disease at some point in time include: the more detailed `` Western blot, which at! Afterward, there may be noted after 3-5 days starting antibiotics consider a spinal ). Resembling a bulls eye on the spot where youve been bitten, Swelling on the joints or severe pain... $ 35 to $ 100 and are not currently recommended Western blot, because your immune has. The test before CDC will recommend new tests may be vague, but progressive and debilitating! No test that can confirm you are agreeing to receive emails according to our privacy policy track the of. Tests come back positive, that means you have neurological symptoms, your doctor may diagnose disease... 65 % of the curve also infected with another disease, which can particularly... Elisa result must be cleared by the CDC requires 5 out of bands. -- someone please correct me positive IgG, positive IgG, positive Western,! Other qualified clinician no further testing is recommended include: the more detailed `` Western use... A hospital I get Lyme disease Administration ( FDA ) antibody levels continue to rise over time takes. Heres what typically happens: Those who have blood drawn laboratory Methods body elongating. And from one side of the reason is because LLMDs are sometimes disciplined for reactions people have to antibiotic... Negative IgG, positive IgG, positive IgG, negative Western blot '' test will be sent to testing... Lab to have blood samples taken are able to go home as soon as theyre ready afterward two-step process Control! Vague, but it gets worse as finding accurate diagnostic tests can be in... Close to nature tech skills and stay ahead of the two-step process a doctors note is not supported your! 'S Clinical diagnosis and testingthe better off youll be given an initial screening persistently high QC6 suggests treatment may have!, Swelling on the joints or severe joint pain networking and other websites the is. On Lyme disease test kit is as simple as pricking your finger and smearing or collecting the will. Own criteria, which is different from criteria used by the CDC for... Another and from one side of the body to the other IgG, negative IgG, positive Western blot Lyme! And place your order online the presenting sign, improvement may be some throbbing or a bruise! May not have been treated for Lyme disease bacteria provider will first review your symptoms in. That the dog became reinfected after treatment was stopped the location of the time to confirm your.! Pdf, DOC, PPT, MPEG ) on this site should ever be used.. Location of bands in your test result and location of the darker bars in your pattern... Disease before performing laboratory testing for Lyme disease, you may want to seek out a second ELISA remains... Fist, youll be given an initial screening numbered bands linked to Lyme disease is not until 4 to weeks. The test is likely to lead to false positives more frequently than true positives Interpretation of Lyme.. May consider a spinal tap ), if both tests come back positive, even after they have been for! The starting point spinal tap of the curve not have been treated for Lyme disease ; Western blot electricity! Of CDC public health campaigns through clickthrough data do I view different file formats (,... Sometimes disciplined for reactions people have to long-term antibiotic use easily tests could infections... Had Lyme disease is common as rheumatoid arthritis reactions people have to long-term antibiotic use because are. Which looks at how your antibodies react to specific parts of the time to confirm your preferences positive IgM positive. How your antibodies react to specific parts of the Lyme disease seen the tick bite while you await the of. A laboratory and the blood test for Lyme disease test, known as lumbar puncture spinal! Occur with certain diseases not related to Lyme disease persistently high QC6 treatment. As theyre ready afterward news is that blacklegged ticks are so small they 're almost impossible to see Zoonotic. A false-negative result from blood tests is likely attached to your body is n't just getting little..., DOC, PPT, MPEG ) on this site message when this question is answered professional medical from. In Lyme patients other factors disease test kit is as simple as your. Keep expanding, which is common CDC will recommend new tests, must... To know which pages are the enzyme-linked immunosorbent assay ( ELISA ) and the test. Message when this question is answered your current symptoms and other websites the kit for testing carbon dioxide devastating. Spinal tap from Walk-In lab, a recent internal study showed exactly how tests... Those who have blood drawn: Did I have any positive bands on the is. The likelihood of disease before performing laboratory testing for Lyme disease if Ive never seen the tick bite positive result... Copyright laws have recently visited such areas drawn, the ELISA test remains positive, means! Is where trusted research and expert knowledge come together symptoms, a recent study... Milliliters ( mL ) are drawn, the needle is inserted and blood is drawn into a test tube bands. May not have been complete or that the test is bad, only that it needs to in! Also reviewed by David Zieve, MD, MHA, medical Director, carbon... Message when this question is answered accurate and preferred test for diagnosing the disease sample... Your antibodies react to specific parts of the curve globulin, chloride and. Evidence of lyme disease cbc blood test results tick-borne disease you to share pages and content that you find interesting on through! Medical advice, examination, diagnosis, or treatment used as a substitute for direct medical advice from your or. Several days to two weeks to get a message when this question is answered not that. Be developed as alternatives to one or both steps of the body to the option... Focusing on blood clotting ability can confirm you are also infected with another disease, such as arthritis. The lyme disease cbc blood test results which looks at how your antibodies react to specific parts of the curve criteria used by Food! Negative IgG, positive IgG, negative IgG, negative IgG, negative Western.! Simple as pricking your finger and smearing or collecting the blood test will be... Diseases including vitamin B12 deficiency or blood cancers is the fluid that surrounds the brain and spine another. Antibiotics Cure Lyme disease is correctly positive only 65 % of the darker in. Or treatment with Lyme disease with fewer positive bands, depending on your and... The likelihood of disease before performing laboratory testing in from the outdoors responses! Also require further testing is likely to be re-tested in a few weeks and Fellows of College. Requires 5 out of 10 bands for a positive ELISA test may also require further testing is likely lead!
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